DETECTION OF NUCLEAR PROTEIN PROFILE CHANGES BY HUMAN METAPNEUMOVIRUS M2-2 PROTEIN USING QUANTITATIVE DIFFERENTIAL PROTEOMICS

Detection of Nuclear Protein Profile Changes by Human Metapneumovirus M2-2 Protein Using Quantitative Differential Proteomics

Human metapneumovirus (hMPV) is a leading cause of lower respiratory infection in pediatric populations globally.This study examined proteomic profile changes in Brushes A549 cells infected with hMPV and two attenuated mutants with deleted PDZ domain-binding motif(s) in the M2-2 protein.These motifs are involved in the interruption of antiviral sig

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S100 Proteins As an Important Regulator of Macrophage Inflammation

The S100 proteins, a family of calcium-binding cytosolic proteins, have a broad range of intracellular and extracellular functions through Electric Jug Element regulating calcium balance, cell apoptosis, migration, proliferation, differentiation, energy metabolism, and inflammation.The intracellular functions of S100 proteins involve interaction wi

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